Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389851 | 0.81 | ALDH1A1 (0.34) | ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL8387402 | 0.78 | NFE2L2 (0.33) | PTGESALOX5 | |
| SCHEMBL8387228 | 0.76 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4E | |
| SCHEMBL31545496 | 0.70 | TP53 (0.38) | TP53 | |
| SCHEMBL24212283 | 0.70 | TP53 (0.38) | TP53 | |
| SCHEMBL30953811 | 0.64 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL1451122 | 0.64 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL1396618 | 0.63 | MGLL (0.52) | ALDH1A1KDM4EMGLLCES2 | |
| SCHEMBL15075072 | 0.62 | TRPV1 (0.39) | MAPT | |
| SCHEMBL4045937 | 0.62 | CTSA (0.34) | ALDH1A1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874579-A | Insecticidal substituted-2.4-diaminoquinazolines related applications | FMC CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| US-5616718-A | USEFUL FOR MAKING 2,4-DIAMINOQUINAZOLINES; INSECTICIDES | FMC CORPORATION (US) | 1997-04-01 | — | — | US | disclosed |
| US-5534518-A | Insecticidal substituted-2,4-diaminoquinazolines | FMC CORPORATION (US) | 1996-07-09 | — | — | US | disclosed |