Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.32 |
| ▸ | HTR3B | O95264 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394566 | 0.84 | FFAR4 (0.34) | FFAR4GPR84HTR3EHTR3BHTR3A | |
| SCHEMBL8390331 | 0.82 | PDE5A (0.34) | GPR84HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8294020 | 0.70 | THRA (0.38) | GPR84CRBNHTR3EHTR3BHTR3A | |
| SCHEMBL8298273 | 0.69 | GPR84 (0.34) | GPR84HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8301428 | 0.67 | THRA (0.34) | GPR84HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8394574 | 0.67 | PDE5A (0.37) | GPR84HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8479287 | 0.64 | PDE5A (0.34) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27972350 | 0.63 | CYP3A4 (0.40) | — | |
| SCHEMBL8395920 | 0.62 | SOAT1 (0.36) | FFAR4HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8362632 | 0.61 | FFAR4 (0.38) | FFAR4THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874023-A | ELECTROOPTICS, DISPLAYS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |