Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | TPH1 | P17752 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839784 | 1.00 | MMP8 (0.44) | MMP8TPH1MAPK1MEN1S1PR4 | |
| SCHEMBL4881644 | 1.00 | MMP8 (0.44) | MMP8TPH1MAPK1MEN1S1PR4 | |
| Hydrochloric Acid SCHEMBL27136330 | 0.98 | TPH1 (0.45) | MMP8TPH1MAPK1MEN1S1PR4 | |
| Hydrochloric Acid SCHEMBL1681290 | 0.98 | TPH1 (0.45) | MMP8TPH1MAPK1MEN1S1PR4 | |
| SCHEMBL7960935 | 0.91 | SLC7A5 (0.48) | MMP8TPH1SLC7A5ALPIPKM | |
| SCHEMBL9967935 | 0.86 | SLC7A5 (0.44) | MMP8TPH1MEN1LMNAMAPT | |
| SCHEMBL20543461 | 0.86 | SLC7A5 (0.44) | MMP8TPH1MEN1LMNAMAPT | |
| SCHEMBL21117856 | 0.86 | SLC7A5 (0.44) | MMP8TPH1MEN1LMNAMAPT | |
| SCHEMBL14139328 | 0.86 | SLC7A5 (0.44) | MMP8TPH1MAPK1LMNAACACB | |
| SCHEMBL2369810 | 0.85 | HDAC1 (0.51) | MEN1MAPTKMT2AACACBSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143052-B2 | Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium | UBE INDUSTRIES, LTD. (JP) | 2012-03-27 | — | — | US | disclosed |