Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392541 | 0.82 | ESR1 (0.36) | PTGS2ESR1PGRCHRM2ADORA3 | |
| SCHEMBL8103928 | 0.78 | PTGS2 (0.54) | PTGS2CHRM2CHRM1 | |
| SCHEMBL7807203 | 0.78 | ALDH1A1 (0.39) | ALDH1A1BLMEGFRNAPRTPOLB | |
| SCHEMBL7811162 | 0.78 | ALDH1A1 (0.39) | ALDH1A1BLMEGFRNAPRTPOLB | |
| SCHEMBL7807201 | 0.78 | ALDH1A1 (0.39) | ALDH1A1BLMEGFRNAPRTPOLB | |
| SCHEMBL8397422 | 0.77 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7808800 | 0.77 | NAPRT (0.51) | ALDH1A1BLMEGFRNAPRTSMN1; SMN2 | |
| SCHEMBL8104528 | 0.75 | PTGS2 (0.54) | PTGS2CHRM2CHRM1 | |
| SCHEMBL5698447 | 0.74 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL29977958 | 0.72 | SMN1; SMN2 (0.59) | ALDH1A1BLMEGFRPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915850-A1 | NOVEL CARBOCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS FOR PREPARING SAME, AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1999-05-19 | — | — | EP | claimed |
| WO-1998005643-A1 | NOVEL CARBOCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS FOR PREPARING SAME, AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | claimed |
| EP-0915850-A1 | NOVEL CARBOCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS FOR PREPARING SAME, AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998005643-A1 | NOVEL CARBOCYCLIC DIARYLMETHYLENE DERIVATIVES, METHODS FOR PREPARING SAME, AND THERAPEUTICAL USES THEREOF | LABORATOIRES UPSA (FR) | 1998-02-12 | — | — | WO | disclosed |
| US-5686460-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | LABORATOIRES UPSA (FR) | 1997-11-11 | — | — | US | disclosed |