Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397670 | 0.99 | OPRM1 (0.46) | OPRM1MEN1KMT2AOPRK1OPRD1 | |
| SCHEMBL8394782 | 0.97 | OPRM1 (0.45) | OPRM1MEN1KMT2AOPRK1OPRD1 | |
| SCHEMBL8394934 | 0.97 | OPRM1 (0.45) | OPRM1MEN1KMT2AOPRK1OPRD1 | |
| SCHEMBL8393611 | 0.95 | MEN1 (0.43) | OPRM1MEN1KMT2AOPRK1OPRD1 | |
| SCHEMBL8396298 | 0.91 | OPRM1 (0.41) | OPRM1OPRK1OPRD1L3MBTL1 | |
| SCHEMBL8396229 | 0.90 | L3MBTL1 (0.43) | OPRM1OPRK1OPRD1L3MBTL1 | |
| SCHEMBL8395642 | 0.88 | L3MBTL1 (0.45) | OPRM1OPRK1OPRD1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8392424 | 0.88 | L3MBTL1 (0.45) | OPRM1OPRK1OPRD1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8391958 | 0.86 | CA1 (0.38) | OPRM1MEN1KMT2AOPRK1OPRD1 | |
| SCHEMBL8394048 | 0.73 | IDO1 (0.47) | OPRM1IDO1LMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |