Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.37 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8392424 | 0.98 | L3MBTL1 (0.45) | L3MBTL1OPRM1OPRK1OPRD1USP2 | |
| SCHEMBL8395642 | 0.98 | L3MBTL1 (0.45) | L3MBTL1OPRM1OPRK1OPRD1USP2 | |
| SCHEMBL8396298 | 0.98 | OPRM1 (0.41) | L3MBTL1OPRM1OPRK1OPRD1USP2 | |
| SCHEMBL8391958 | 0.94 | CA1 (0.38) | L3MBTL1OPRM1OPRK1OPRD1EPHX2 | |
| SCHEMBL8397670 | 0.91 | OPRM1 (0.46) | L3MBTL1OPRM1OPRK1OPRD1EPHX2 | |
| SCHEMBL8394782 | 0.90 | OPRM1 (0.45) | L3MBTL1OPRM1OPRK1OPRD1USP2 | |
| SCHEMBL8394934 | 0.90 | OPRM1 (0.45) | L3MBTL1OPRM1OPRK1OPRD1USP2 | |
| SCHEMBL8395298 | 0.90 | OPRM1 (0.44) | L3MBTL1OPRM1OPRK1OPRD1 | |
| SCHEMBL8393611 | 0.85 | MEN1 (0.43) | OPRM1OPRK1OPRD1EPHX2 | |
| SCHEMBL28601901 | 0.78 | TSHR (0.38) | L3MBTL1OPRM1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |