Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396219 | 0.89 | SMN1; SMN2 (0.51) | OXTRKMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL8395962 | 0.87 | MDM2 (0.43) | MAPTKMT2ASMN1; SMN2FDFT1HTT | |
| SCHEMBL8400488 | 0.85 | SMN1; SMN2 (0.42) | MAPTTP53POLBRAB9AOXTR | |
| SCHEMBL8400320 | 0.85 | SMN1; SMN2 (0.46) | MAPTRAB9AKMT2ASMN1; SMN2HPGD | |
| SCHEMBL8399249 | 0.84 | HPGD (0.47) | MAPTTP53GAAPOLBKMT2A | |
| SCHEMBL8399145 | 0.84 | ATM (0.41) | MAPTGAAPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL8399081 | 0.84 | ALDH1A1 (0.47) | MAPTTP53POLBRAB9AKMT2A | |
| SCHEMBL8400558 | 0.84 | SMN1; SMN2 (0.54) | MAPTTP53KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8400240 | 0.82 | MLYCD (0.40) | MAPTTP53POLBKMT2ASMN1; SMN2 | |
| SCHEMBL8399007 | 0.82 | SMN1; SMN2 (0.37) | MAPTGAAKMT2ASMN1; SMN2FDFT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |