Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLQ | O75417 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400320 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL8398077 | 0.87 | SMN1; SMN2 (0.72) | SMN1; SMN2TP53POLQKMT2AMEN1 | |
| SCHEMBL8399081 | 0.86 | ALDH1A1 (0.47) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL8395962 | 0.86 | MDM2 (0.43) | SMN1; SMN2KMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL8399145 | 0.86 | ATM (0.41) | SMN1; SMN2KMT2AALDH1A1TSHRHPGD | |
| SCHEMBL8399249 | 0.86 | HPGD (0.47) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL8400306 | 0.85 | KMT2A (0.43) | SMN1; SMN2TP53POLQKMT2AMEN1 | |
| SCHEMBL8400465 | 0.84 | MTNR1A (0.52) | TP53KMT2AHSD17B10 | |
| SCHEMBL8399042 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2POLQKMT2AMEN1ALDH1A1 | |
| SCHEMBL8399140 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2KMT2AMEN1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |