Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396137 | 0.90 | HSD17B10 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL8394747 | 0.89 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL8396010 | 0.88 | AGTR1 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL8391781 | 0.88 | AGTR1 (0.51) | TP53AGTR1AGTR2MAPTPPARG | |
| SCHEMBL8392916 | 0.87 | AGTR1 (0.46) | TP53AGTR1AGTR2MAPTSMN1; SMN2 | |
| SCHEMBL8394541 | 0.86 | AGTR1 (0.44) | TP53AGTR1AGTR2MAPTSMN1; SMN2 | |
| SCHEMBL8397132 | 0.86 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL8392836 | 0.85 | LMNA (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL8392917 | 0.85 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8392422 | 0.85 | AGTR1 (0.56) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |