Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396137 | 0.94 | HSD17B10 (0.47) | AGTR1AGTR2PPARG | |
| SCHEMBL8394679 | 0.93 | AGTR1 (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL8394747 | 0.92 | AGTR1 (0.46) | AGTR1AGTR2PPARG | |
| SCHEMBL8392422 | 0.90 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL8397132 | 0.89 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL8392917 | 0.88 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8392836 | 0.88 | LMNA (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL8395697 | 0.88 | TP53 (0.51) | AGTR1AGTR2PPARG | |
| SCHEMBL8396737 | 0.87 | PPARG (0.49) | AGTR1AGTR2PPARG | |
| SCHEMBL8393639 | 0.87 | PPARG (0.57) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |