Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 6/20 | 0.66 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.66 |
| ▸ | FPR3 | P25089 | 1/20 | 0.66 |
| ▸ | GPR183 | P32249 | 1/20 | 0.66 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8590397 | 0.89 | NTSR1 (0.51) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8591220 | 0.84 | NTSR1 (0.45) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8590175 | 0.82 | NTSR1 (0.44) | NTSR1NTSR2FPR3GPR183SORT1 | |
| Reminertant SCHEMBL29376784 | 0.79 | NTSR1 (1.00) | NTSR1NTSR2FPR3GPR183SORT1 | |
| Reminertant SCHEMBL1650932 | 0.79 | NTSR1 (1.00) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8591745 | 0.77 | NTSR1 (0.43) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL7556717 | 0.77 | NTSR1 (0.81) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9077529 | 0.77 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL729750 | 0.76 | NTSR1 (0.71) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8591555 | 0.76 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955474-A | ANTIEDEMA AGENTS OR DIURETIC ANTAGONIST | SANOFI (FR) | 1999-09-21 | — | — | US | claimed |
| US-5955474-A | ANTIEDEMA AGENTS OR DIURETIC ANTAGONIST | SANOFI (FR) | 1999-09-21 | — | — | US | disclosed |
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |