Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 7/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | GPR183 | P32249 | 1/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591220 | 0.89 | NTSR1 (0.45) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8395699 | 0.89 | NTSR1 (0.66) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8590175 | 0.86 | NTSR1 (0.44) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8591745 | 0.82 | NTSR1 (0.43) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8590399 | 0.79 | NTSR1 (0.80) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8589011 | 0.73 | NTSR1 (0.51) | NTSR1NTSR2FPR3GPR183SORT1 | |
| Reminertant SCHEMBL1650932 | 0.68 | NTSR1 (1.00) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL8591222 | 0.67 | NTSR1 (0.72) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9153323 | 0.67 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 | |
| SCHEMBL9077529 | 0.65 | NTSR1 (0.69) | NTSR1NTSR2FPR3GPR183SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744493-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |
| US-5744491-A | POSSESS ACTIVITY WITH RESPECT TO THE CENTRAL NERVOUS SYSTEM, THE CARDIOVASCULAR SYSTEM AND THE GASTROINTESTINAL SYSTEM | SANOFI (FR) | 1998-04-28 | — | — | US | disclosed |