Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 8/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 8/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 8/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396369 | 0.79 | CA3 (0.66) | CA3CA5ACA5BCA12CA2 | |
| SCHEMBL8656849 | 0.79 | CA3 (0.66) | CA3CA5ACA5BCA12CA2 | |
| SCHEMBL8654037 | 0.70 | APP (0.46) | HDAC3HDAC1HDAC2HDAC8ALDH1A1 | |
| SCHEMBL8654039 | 0.70 | APP (0.46) | HDAC3HDAC1HDAC2HDAC8ALDH1A1 | |
| SCHEMBL3373746 | 0.69 | MME (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL14423531 | 0.69 | MME (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3880596 | 0.69 | EPHX1 (0.52) | ALDH1A1POLBSMN1; SMN2EPHX1 | |
| SCHEMBL3837907 | 0.69 | CA12 (0.49) | CA12CA2CA4CA9ALDH1A1 | |
| SCHEMBL9632174 | 0.69 | POLB (0.57) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8699335 | 0.68 | POLB (0.55) | CA3CA5ACA5BCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883132-A | MULTISTAGE REACTION OF AMIDATION, ACTIVATION, COUPLING AND HYDROLYSIS | FOURNIER INDUSTRIE ET SANTE (FR) | 1999-03-16 | — | — | US | disclosed |