Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8393294 | 0.88 | AGTR2 (0.47) | AGTR2AGTR1 | |
| SCHEMBL8393575 | 0.87 | AGTR2 (0.44) | AGTR2AGTR1LMNAMAPK1PPARG | |
| SCHEMBL8392455 | 0.87 | AGTR2 (0.43) | AGTR2AGTR1 | |
| SCHEMBL8392422 | 0.86 | AGTR1 (0.56) | AGTR2AGTR1PPARG | |
| Water SCHEMBL8396080 | 0.86 | AGTR1 (0.41) | AGTR2AGTR1PPARG | |
| SCHEMBL8394867 | 0.85 | AGTR1 (0.41) | AGTR2AGTR1 | |
| SCHEMBL8396608 | 0.85 | PPARG (0.45) | ALDH1A1AGTR2AGTR1PPARG | |
| Water SCHEMBL8395451 | 0.84 | AGTR2 (0.41) | AGTR2AGTR1PPARG | |
| SCHEMBL8396601 | 0.83 | AGTR1 (0.48) | AGTR2AGTR1PPARG | |
| SCHEMBL8393639 | 0.83 | PPARG (0.57) | AGTR2AGTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |