Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 5/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.47 |
| ▸ | APLNR | P35414 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396647 | 0.88 | ALDH1A1 (0.48) | AGTR2AGTR1 | |
| SCHEMBL8391541 | 0.88 | AGTR1 (0.41) | AGTR2AGTR1APLNR | |
| SCHEMBL8396743 | 0.86 | AGTR1 (0.48) | AGTR2AGTR1 | |
| SCHEMBL8395685 | 0.86 | AGTR1 (0.45) | AGTR2AGTR1APLNR | |
| SCHEMBL8393575 | 0.85 | AGTR2 (0.44) | AGTR2AGTR1 | |
| SCHEMBL8392455 | 0.84 | AGTR2 (0.43) | AGTR2AGTR1 | |
| SCHEMBL8392422 | 0.84 | AGTR1 (0.56) | AGTR2AGTR1 | |
| SCHEMBL8395705 | 0.83 | AGTR2 (0.43) | AGTR2AGTR1 | |
| SCHEMBL8393675 | 0.82 | PPARG (0.49) | AGTR2AGTR1 | |
| SCHEMBL8395220 | 0.82 | PPARG (0.49) | AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |