Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15975483 | 0.78 | EPHX2 (0.53) | EPHX2EPHX1POLB | |
| SCHEMBL1237952 | 0.71 | EPHX2 (0.54) | EPHX2EPHX1SIGMAR1POLB | |
| SCHEMBL3079393 | 0.71 | EPHX2 (0.58) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL3081626 | 0.69 | EPHX2 (0.47) | EPHX2EPHX1SIGMAR1POLB | |
| Hydrochloric Acid SCHEMBL6158167 | 0.69 | EPHX2 (0.56) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL6720885 | 0.67 | FAAH (0.42) | EPHX2EPHX1 | |
| SCHEMBL3069081 | 0.67 | EPHX2 (0.54) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL8920876 | 0.67 | GRIN2D (0.38) | EPHX2EPHX1SIGMAR1POLB | |
| SCHEMBL6681638 | 0.66 | EPHX2 (0.52) | EPHX2EPHX1SIGMAR1 | |
| SCHEMBL7401097 | 0.66 | THRB (0.42) | EPHX2EPHX1SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |