Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153629 | 0.80 | GRIN2D (0.44) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3071615 | 0.76 | GRIN2D (0.44) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL27925445 | 0.75 | MEN1 (0.39) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6687969 | 0.74 | THRB (0.39) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15975483 | 0.74 | EPHX2 (0.53) | EPHX1EPHX2ALDH1A1LMNAPOLB | |
| SCHEMBL11076670 | 0.73 | GRIN2D (0.52) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL22409653 | 0.70 | ALDH1A1 (0.42) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6687971 | 0.70 | GRIN2D (0.42) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8779303 | 0.68 | THRB (0.38) | THRBCYP2C9GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28751556 | 0.67 | GRIN2D (0.50) | THRBCYP2C9GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999222-B | Adamantyl oxadiazole-containing compound and preparation method and application thereof | 贵州大学 | 2023-06-27 | — | — | CN | disclosed |
| CN-113999222-A | Adamantyl oxadiazole-containing compounds and preparation method and application thereof | 贵州大学 | 2022-02-01 | — | — | CN | disclosed |
| EP-0517913-A1 | INHIBITIONS OF ENDOTHELIN FORMATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992012170-A1 | INHIBITIONS OF ENDOTHELIN FORMATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-07-23 | — | — | WO | disclosed |
| EP-0134986-B1 | BIOLOGICALLY ACTIVE HEPTAPEPTIDES, AGENTS THEREOF AND THEIR USE | FARMITALIA CARLO ERBA S.r.l. (IT) | 1989-12-27 | — | — | EP | disclosed |
| US-4567162-A | ANIMAL GROWTH PROMOTERS | FARMITALIA CARLO ERBA (IT) | 1986-01-28 | — | — | US | disclosed |
| EP-0134986-A2 | Biologically active heptapeptides, agents thereof and their use | FARMITALIA CARLO ERBA S.r.l. (IT) | 1985-03-27 | — | — | EP | disclosed |
| US-4491541-A | Peptides | FARMITALIA CARLO ERBA | 1985-01-01 | — | — | US | disclosed |
| US-4474765-A | Biologically active peptides | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-10-02 | — | — | US | disclosed |
| US-4350627-A | Biologically active peptides | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-09-21 | — | — | US | disclosed |