Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8428364 | 0.77 | MEN1 (0.40) | MEN1MAPTMAPK1KMT2A | |
| SCHEMBL6156344 | 0.72 | — | — | |
| SCHEMBL6155659 | 0.72 | EPHX2 (0.33) | MEN1MAPTMAPK1KMT2A | |
| SCHEMBL8398462 | 0.66 | — | — | |
| SCHEMBL8400958 | 0.66 | — | — | |
| SCHEMBL8843240 | 0.66 | SIGMAR1 (0.41) | — | |
| SCHEMBL9316000 | 0.66 | SIGMAR1 (0.41) | — | |
| SCHEMBL6156028 | 0.64 | MAPT (0.41) | MEN1MAPTMAPK1KMT2A | |
| SCHEMBL8401612 | 0.63 | KDM4E (0.35) | MEN1MAPTKMT2A | |
| SCHEMBL8428530 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |