Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397958 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CA1CA2HPGDLMNA | |
| SCHEMBL8397951 | 1.00 | ALDH1A1 (0.47) | ALDH1A1CA1CA2HPGDLMNA | |
| SCHEMBL8399606 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CA1CA2HPGDLMNA | |
| SCHEMBL14193309 | 0.89 | NR1D1 (0.48) | ALDH1A1HPGDTSHRNR1D1MAPT | |
| SCHEMBL4815395 | 0.89 | NR1D1 (0.48) | ALDH1A1HPGDTSHRNR1D1MAPT | |
| SCHEMBL19318895 | 0.88 | HPGD (0.49) | ALDH1A1CA1CA2HPGDTSHR | |
| SCHEMBL8399607 | 0.88 | FABP7 (0.50) | ALDH1A1CA1CA2HPGDTSHR | |
| SCHEMBL8401362 | 0.86 | MAPT (0.47) | ALDH1A1HPGDLMNATSHRNR1D1 | |
| SCHEMBL4822683 | 0.86 | MAPT (0.47) | ALDH1A1HPGDLMNATSHRNR1D1 | |
| SCHEMBL8401366 | 0.86 | MAPT (0.47) | ALDH1A1HPGDLMNATSHRNR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869518-A | USEFUL IN THE TREATMENT OF OBESITY AND HYPERGLYCEMIA | SYNTHELABO (FR) | 1999-02-09 | — | — | US | disclosed |