Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | VDR | P11473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15468472 | 0.84 | ENPP1 (0.55) | MAPTALDH1A1F2KDM4EVDR | |
| SCHEMBL8499355 | 0.84 | ENPP1 (0.55) | MAPTALDH1A1F2KDM4EVDR | |
| SCHEMBL3621448 | 0.83 | CA2 (0.54) | MAPTALDH1A1F2KDM4EVDR | |
| Iodide SCHEMBL28609407 | 0.82 | TDP1 (0.51) | MAPTALDH1A1TDP1L3MBTL1GAA | |
| SCHEMBL3082396 | 0.82 | TDP1 (0.51) | MAPTALDH1A1F2TDP1L3MBTL1 | |
| SCHEMBL22187505 | 0.82 | CA2 (0.56) | MAPTALDH1A1CA2KMT2ASMN1; SMN2 | |
| SCHEMBL10446681 | 0.81 | ALDH1A1 (0.55) | MAPTALDH1A1F2KDM4EVDR | |
| SCHEMBL8393962 | 0.81 | TDP1 (0.47) | MAPTALDH1A1F2TDP1L3MBTL1 | |
| SCHEMBL9547096 | 0.81 | ADRB2 (0.45) | MAPTALDH1A1F2KDM4EVDR | |
| SCHEMBL19146 | 0.80 | TDP1 (0.73) | MAPTALDH1A1KDM4ETDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773235-B1 | Polymerization of alpha-olefins | MITSUBISHI CHEM CORP (JP) | 1999-05-26 | — | — | EP | disclosed |
| EP-0759445-B1 | Catalyst for olefin polymerization and method for producing olefin polymers using the same | MITSUBISHI CHEM CORP (JP) | 1999-03-17 | — | — | EP | disclosed |
| EP-0773235-A1 | Polymerization of alpha-olefins | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0759445-A1 | Catalyst for olefin polymerization and method for producing olefin polymers using the same | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-02-26 | — | — | EP | disclosed |