Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218609 | 0.92 | TSHR (0.32) | TSHRMEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL10552009 | 0.79 | — | — | |
| SCHEMBL3940066 | 0.78 | ALDH1A1 (0.35) | TSHRMEN1POLBKMT2APAOX | |
| SCHEMBL16317707 | 0.77 | ADH1A (0.39) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL1307259 | 0.76 | USP2 (0.36) | TSHRMEN1POLBKMT2APAOX | |
| SCHEMBL232247 | 0.74 | MEN1 (0.39) | TSHRMEN1POLBKMT2APAOX | |
| SCHEMBL15052708 | 0.74 | MEN1 (0.39) | TSHRMEN1POLBKMT2APAOX | |
| SCHEMBL2916 | 0.73 | — | — | |
| SCHEMBL6991188 | 0.72 | TSHR (0.33) | TSHRMEN1POLBKMT2A | |
| SCHEMBL26744523 | 0.72 | ALDH1A1 (0.35) | TSHRMEN1POLBKMT2APAOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485633-B2 | RNA polymerase, HCV metalloprotease, HCV serine protease, HCV polymerase, HCV helicase inhibitor; liver disease; (+/-)-8-Cyclohexyl-N-4-(morpholinosulfonyl)-1,1a,2,12b-tetrahydro-11-methoxy-1a-(3-methyl-3,8-diazabicyclo[3.2.1]octane-8-carbonyl)cycloprop[d]indolo[2,1-a][2]benzazepine-5-carboxamide | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-02-03 | — | — | US | disclosed |
| US-5973094-A | Functional polymers | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0794199-A2 | Novel functional polymers | WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) | 1997-09-10 | — | — | EP | disclosed |