SCHEMBL8398151

SCHEMBL8398151

C=C1C(=O)OC(C)(C)CC1C

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MITF O75030 1/20 0.35
CYP3A4 P08684 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
UBE2D3 P61077 1/20 0.33
MEN1 O00255 1/20 0.32
GAA P10253 1/20 0.32
THRB P10828 1/20 0.32
KMT2A Q03164 1/20 0.32
NPC1 O15118 1/20 0.31
MAPT P10636 1/20 0.31
XBP1 P17861 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
MDM2 Q00987 1/20 0.31
PTGS2 P35354 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9717735 0.73
SCHEMBL14272279 0.73
SCHEMBL12121152 0.72 PTPN11 (0.32) MEN1GAATHRBKMT2A
SCHEMBL8394026 0.67 MITF (0.34) MITF
SCHEMBL3947301 0.64
SCHEMBL76598 0.64
SCHEMBL3944987 0.64
SCHEMBL2376391 0.64
SCHEMBL10192298 0.62 L3MBTL1 (0.34) NPC1MAPT
SCHEMBL17625111 0.61 MEN1 (0.40) CYP3A4LMNATP53MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722960-B1 Copolymers for preparing cast glass, or molding materials for preparing heat stable shaped articles AGOMER GES MIT BESCHRAENKTER H (DE) 1999-06-02 EP disclosed
US-5880235-A POLYMER PREPARED BY COPOLYMERIZING ALPHA-METHYLENE-GAMMA-BUTYROLACTONE AND VINYLICALLY UNSATURATED MONOMER AGOMER GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1999-03-09 US disclosed
EP-0722960-A2 Copolymers for preparing cast glass, or molding materials for preparing heat stable shaped articles Degussa Aktiengesellschaft (DE) 1996-07-24 EP disclosed