Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 4/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398066 | 0.88 | KDM4E (0.41) | AKR1B1KDM4EMEN1KMT2ATRPM5 | |
| SCHEMBL8399039 | 0.85 | ADRA2C (0.40) | AKR1B1KDM4EMEN1KMT2AADRA2B | |
| SCHEMBL8395348 | 0.85 | AKR1B1 (0.39) | AKR1B1KDM4EMEN1KMT2ATRPM5 | |
| SCHEMBL8398150 | 0.83 | MEN1 (0.46) | AKR1B1KDM4EMEN1KMT2AADRA2B | |
| SCHEMBL8397959 | 0.82 | ADRA1D (0.40) | AKR1B1KDM4EMEN1KMT2AADRA2B | |
| SCHEMBL8395550 | 0.81 | L3MBTL1 (0.44) | AKR1B1KDM4EMEN1KMT2AROCK2 | |
| SCHEMBL8398085 | 0.81 | AKR1B1 (0.44) | AKR1B1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8400556 | 0.81 | AKR1B1 (0.45) | AKR1B1 | |
| SCHEMBL8396300 | 0.80 | MEN1 (0.43) | AKR1B1MEN1KMT2ATRPM5ROCK2 | |
| SCHEMBL8396281 | 0.80 | KMT2A (0.43) | AKR1B1KDM4EMEN1KMT2ATRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |