Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24022445 | 0.82 | ALDH1A1 (0.55) | TERTLMNAHPGDPOLBMEN1 | |
| SCHEMBL4955344 | 0.82 | S1PR4 (0.43) | TERTLMNAHPGDPOLBMEN1 | |
| SCHEMBL1232491 | 0.81 | MAPT (0.58) | LMNAPOLBMEN1KMT2APKM | |
| SCHEMBL25620098 | 0.77 | ALDH1A1 (0.59) | LMNAHPGDKMT2ATSHRALOX15 | |
| SCHEMBL24849174 | 0.77 | LMNA (0.49) | LMNAHPGDPOLBMEN1KMT2A | |
| SCHEMBL11723023 | 0.76 | ALDH1A1 (0.54) | HPGDPOLBMEN1KMT2ATSHR | |
| SCHEMBL7124281 | 0.76 | TERT (0.42) | TERTLMNAPOLBMEN1KMT2A | |
| SCHEMBL11723693 | 0.75 | HPGD (0.51) | LMNAHPGDKMT2ATSHRRAB9A | |
| SCHEMBL28829667 | 0.75 | LMNA (0.51) | LMNAHPGDPOLBMEN1KMT2A | |
| SCHEMBL21261833 | 0.75 | HPGD (0.77) | LMNAHPGDMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915834-A1 | METHOD AND COMPOSITIONS FOR PRODUCING ANALGESIA | ELAN PHARMACEUTICALS, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997033860-A1 | METHOD AND COMPOSITIONS FOR PRODUCING ANALGESIA | NEUREX CORPORATION (US) | 1997-09-18 | — | — | WO | disclosed |