Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896797 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2PTGDR2TSHRMAPTNPC1 | |
| SCHEMBL7646069 | 1.00 | SMN1; SMN2 (0.40) | SMN1; SMN2PTGDR2TSHRMAPTNPC1 | |
| SCHEMBL8397935 | 0.92 | MRGPRX4 (0.41) | SMN1; SMN2TSHRMAPTNPC1RAB9A | |
| SCHEMBL8519544 | 0.90 | PTGDR2 (0.38) | SMN1; SMN2PTGDR2TSHRMAPTNPC1 | |
| SCHEMBL8396050 | 0.89 | RECQL (0.44) | PTGDR2MAPTTDP1CYP1A2ALDH1A1 | |
| SCHEMBL8398007 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2PTGDR2TSHRMAPTNPC1 | |
| SCHEMBL8424504 | 0.85 | PTGDR2 (0.42) | SMN1; SMN2PTGDR2TSHRMAPTNPC1 | |
| SCHEMBL8400501 | 0.84 | FFAR1 (0.40) | MAPTNPC1ALDH1A1HTTLMNA | |
| SCHEMBL9279878 | 0.84 | PTGDR2 (0.41) | SMN1; SMN2PTGDR2TSHRMAPTNPC1 | |
| SCHEMBL8397983 | 0.84 | TDP1 (0.41) | SMN1; SMN2MAPTNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |