Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279878 | 0.89 | PTGDR2 (0.41) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL7646069 | 0.85 | SMN1; SMN2 (0.40) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL896797 | 0.85 | SMN1; SMN2 (0.40) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL8399059 | 0.85 | SMN1; SMN2 (0.40) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL8420326 | 0.84 | TSHR (0.43) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL8519544 | 0.84 | PTGDR2 (0.38) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL30000915 | 0.83 | ALDH1A1 (0.44) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL8421330 | 0.82 | SMN1; SMN2 (0.46) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL8422352 | 0.82 | TSHR (0.44) | PTGDR2TSHRSMN1; SMN2ALDH1A1CYP2C9 | |
| SCHEMBL8422699 | 0.78 | SMN1; SMN2 (0.41) | PTGDR2TSHRSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679967-B | Reductase, gene thereof, and method for using same | SUMITOMO CHEMICAL CO | 2013-06-12 | — | — | CN | disclosed |
| US-5948819-A | α-substituted phenylacetic acid derivative, its production and agricultural fungicide containing it | SHIONOGI & CO., LTD (JP) | 1999-09-07 | — | — | US | disclosed |
| US-5693859-A | REACTING ORTHO-SUBSTITUTED PHENYL ALPHA-KETO ACID HALIDE WITH AN AMINE YIELDS SUBSTITUTED PHENYL ALPHA-KETAMIDE | SHIONOGI & CO., LTD. (JP) | 1997-12-02 | — | — | US | disclosed |
| US-5502252-A | FUNGICIDES FOR RICE AND CUCUMBERS | SHIONOGI & CO., LTD. (JP) | 1996-03-26 | — | — | US | disclosed |