SCHEMBL8397935

SCHEMBL8397935

CON=CC(=O)N(C)c1ccccc1COc1ccc(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 1/20 0.41
RECQL P46063 1/20 0.39
FFAR4 Q5NUL3 7/20 0.38
FFAR1 O14842 4/20 0.38
CD274 Q9NZQ7 2/20 0.37
HIF1A Q16665 1/20 0.37
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
TSHR P16473 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP3 P42574 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7646069 0.92 SMN1; SMN2 (0.40) RECQLNPC1LMNAMAPTTSHR
SCHEMBL8399059 0.92 SMN1; SMN2 (0.40) RECQLNPC1LMNAMAPTTSHR
SCHEMBL896797 0.92 SMN1; SMN2 (0.40) RECQLNPC1LMNAMAPTTSHR
SCHEMBL8396361 0.90 ANO1 (0.45) MRGPRX4FFAR4FFAR1MAPTTDP1
SCHEMBL8396050 0.89 RECQL (0.44) RECQLMAPTL3MBTL1TDP1
SCHEMBL8395678 0.88 MRGPRX4 (0.39) MRGPRX4RECQLFFAR4FFAR1HIF1A
SCHEMBL8400501 0.84 FFAR1 (0.40) FFAR4FFAR1HIF1AHPGDNPC1
SCHEMBL8398841 0.84 L3MBTL1 (0.42) RECQLNPC1LMNAMAPTTSHR
SCHEMBL8396306 0.84 HIF1A (0.42) HIF1ALMNAMAPTSMN1; SMN2L3MBTL1
SCHEMBL8399047 0.84 GRM5 (0.39) CD274HIF1AHPGDLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644183-B1 Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1999-06-02 EP disclosed
US-5498792-A Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1996-03-12 US disclosed
EP-0644183-A2 Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1995-03-22 EP disclosed