SCHEMBL8400501

SCHEMBL8400501

CON=CC(=O)N(C)c1ccccc1COc1ccc(C)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.40
FFAR4 Q5NUL3 2/20 0.40
MAOB P27338 4/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 2/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
MAPT P10636 2/20 0.36
PTPRC P08575 1/20 0.36
PTPN1 P18031 1/20 0.36
HTT P42858 1/20 0.36
MAOA P21397 1/20 0.36
HIF1A Q16665 1/20 0.36
PTGER1 P34995 1/20 0.35
PARP10 Q53GL7 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8399075 0.90 KMT2A (0.42) FFAR1FFAR4MAOBMEN1KMT2A
SCHEMBL8846363 0.90 PTGER4 (0.42) FFAR1FFAR4KMT2ALMNANPC1
SCHEMBL8399047 0.90 GRM5 (0.39) MAOBLMNAALDH1A1HPGDMAPT
SCHEMBL8397983 0.88 TDP1 (0.41) MAOBNPC1ALDH1A1HPGDMAPT
SCHEMBL8396306 0.88 HIF1A (0.42) MAOBMEN1KMT2ALMNAALDH1A1
SCHEMBL8398044 0.87 FFAR1 (0.42) FFAR1FFAR4MAOBMAOAHIF1A
SCHEMBL8399105 0.86 FFAR1 (0.39) FFAR1FFAR4MAOBMEN1KMT2A
SCHEMBL8399059 0.84 SMN1; SMN2 (0.40) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL7646069 0.84 SMN1; SMN2 (0.40) MEN1KMT2ALMNANPC1ALDH1A1
SCHEMBL8397935 0.84 MRGPRX4 (0.41) FFAR1FFAR4LMNANPC1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644183-B1 Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1999-06-02 EP disclosed
US-5498792-A Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1996-03-12 US disclosed
EP-0644183-A2 Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1995-03-22 EP disclosed