Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395954 | 0.89 | HIF1A (0.41) | HIF1AMAOBMEN1KMT2A | |
| SCHEMBL8398993 | 0.89 | KMT2A (0.41) | MAOBMEN1KMT2APARP15PARP10 | |
| SCHEMBL8399231 | 0.88 | HIF1A (0.44) | HIF1AMRGPRX4SLC6A2SLC6A4HTR1A | |
| SCHEMBL8396214 | 0.87 | MCL1 (0.43) | HIF1AMRGPRX4MAOBNR4A2 | |
| SCHEMBL8396046 | 0.85 | MAOB (0.40) | HIF1AMAOBNR4A2MEN1KMT2A | |
| SCHEMBL8399054 | 0.85 | MEN1 (0.43) | DCPSMEN1KMT2A | |
| SCHEMBL8400198 | 0.84 | TDP1 (0.40) | HIF1AMAOBMEN1KMT2A | |
| SCHEMBL8400207 | 0.84 | CYP3A4 (0.38) | HIF1AMAOBMEN1KMT2A | |
| SCHEMBL8399105 | 0.83 | FFAR1 (0.39) | HIF1ATSHRMAOBMEN1KMT2A | |
| SCHEMBL9241220 | 0.83 | RECQL (0.41) | HIF1ATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |