Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395954 | 0.92 | HIF1A (0.41) | CYP3A4LMNAHIF1ASMN1; SMN2MAPT | |
| SCHEMBL8399105 | 0.90 | FFAR1 (0.39) | CYP3A4LMNAHIF1AKDM4EALDH1A1 | |
| SCHEMBL8400198 | 0.87 | TDP1 (0.40) | CYP3A4LMNAHIF1ASMN1; SMN2KDM4E | |
| SCHEMBL8399047 | 0.87 | GRM5 (0.39) | LMNAHIF1ASMN1; SMN2F2GRM5 | |
| SCHEMBL9241220 | 0.85 | RECQL (0.41) | CYP3A4LMNAHIF1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8398993 | 0.85 | KMT2A (0.41) | LMNAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8395678 | 0.84 | MRGPRX4 (0.39) | CYP3A4LMNAHIF1ASMN1; SMN2KDM4E | |
| SCHEMBL8398007 | 0.84 | SMN1; SMN2 (0.39) | CYP3A4LMNASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8399090 | 0.84 | HIF1A (0.43) | HIF1AMEN1KMT2AMAOB | |
| SCHEMBL8398724 | 0.84 | NISCH (0.38) | CYP3A4LMNAHIF1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |