Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399105 | 0.90 | FFAR1 (0.39) | KMT2AMEN1MAOBALDH1A1GAA | |
| SCHEMBL8399090 | 0.89 | HIF1A (0.43) | KMT2AMEN1MAOBPARP10PARP15 | |
| SCHEMBL8398891 | 0.89 | FFAR1 (0.41) | MAOBFFAR1FFAR4 | |
| SCHEMBL8399129 | 0.87 | LMNA (0.41) | KMT2AMEN1MAOBALDH1A1GAA | |
| SCHEMBL8399075 | 0.87 | KMT2A (0.42) | KMT2AMEN1MAOBPOLBALDH1A1 | |
| SCHEMBL8398724 | 0.86 | NISCH (0.38) | KMT2AMEN1POLBALDH1A1GAA | |
| SCHEMBL8396046 | 0.86 | MAOB (0.40) | KMT2AMEN1MAOBPARP14PARP10 | |
| SCHEMBL8399054 | 0.85 | MEN1 (0.43) | KMT2AMEN1POLBALDH1A1GAA | |
| SCHEMBL8400198 | 0.85 | TDP1 (0.40) | KMT2AMEN1MAOBPOLBLMNA | |
| SCHEMBL8400207 | 0.85 | CYP3A4 (0.38) | KMT2AMEN1MAOBPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644183-B1 | Process of producing N-alkylacetamides | SHIONOGI & CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5498792-A | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0644183-A2 | Process of producing N-alkylacetamides | SHIONOGI & CO., LTD. (JP) | 1995-03-22 | — | — | EP | disclosed |