SCHEMBL8399105

SCHEMBL8399105

CCN(C(=O)C=NOC)c1ccccc1COc1ccc(C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.39
FFAR4 Q5NUL3 2/20 0.39
MAOB P27338 3/20 0.38
CYP3A4 P08684 2/20 0.38
LMNA P02545 2/20 0.38
PTGER1 P34995 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TRPM8 Q7Z2W7 2/20 0.37
HPGD P15428 2/20 0.36
HTT P42858 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LTB4R Q15722 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8398993 0.90 KMT2A (0.41) FFAR1FFAR4MAOBLMNAMEN1
SCHEMBL8400207 0.90 CYP3A4 (0.38) MAOBCYP3A4LMNAMEN1KMT2A
SCHEMBL8395954 0.88 HIF1A (0.41) MAOBCYP3A4LMNAMEN1KMT2A
SCHEMBL8400198 0.88 TDP1 (0.40) MAOBCYP3A4LMNAMEN1KMT2A
SCHEMBL8398891 0.87 FFAR1 (0.41) FFAR1FFAR4MAOBTRPM8MAOA
SCHEMBL8400501 0.86 FFAR1 (0.40) FFAR1FFAR4MAOBLMNAPTGER1
SCHEMBL8398007 0.85 SMN1; SMN2 (0.39) CYP3A4LMNAMEN1KMT2AHTT
SCHEMBL8395678 0.85 MRGPRX4 (0.39) FFAR1FFAR4CYP3A4LMNAMEN1
SCHEMBL8398724 0.85 NISCH (0.38) CYP3A4LMNAMEN1KMT2AHPGD
SCHEMBL8395408 0.84 CYP3A4 (0.43) CYP3A4LMNAMEN1KMT2ATRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644183-B1 Process of producing N-alkylacetamides SHIONOGI & CO (JP) 1999-06-02 EP disclosed
US-5498792-A Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1996-03-12 US disclosed
EP-0644183-A2 Process of producing N-alkylacetamides SHIONOGI & CO., LTD. (JP) 1995-03-22 EP disclosed