Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395207 | 0.92 | LTB4R2 (0.39) | KMT2ANPC1RAB9ALMNAPOLB | |
| SCHEMBL8399206 | 0.90 | SMN1; SMN2 (0.40) | MTNR1AMTNR1BHSD17B1HSD17B2NPC1 | |
| SCHEMBL8399251 | 0.90 | TSHR (0.40) | NPC1RAB9ALMNAPOLBPTGDR2 | |
| SCHEMBL8398137 | 0.89 | RAB9A (0.40) | KMT2AF2NPC1RAB9ALMNA | |
| SCHEMBL8399085 | 0.89 | LTB4R2 (0.40) | KMT2ANPC1LMNAPTGDR2LTB4R2 | |
| SCHEMBL8398176 | 0.88 | AKR1B1 (0.40) | MTNR1AMTNR1BKMT2AF2PTGDR2 | |
| SCHEMBL8399483 | 0.88 | HDAC6 (0.39) | NPC1RAB9ALMNALTB4R2NOS2 | |
| SCHEMBL8395274 | 0.87 | AKR1B1 (0.37) | NPC1RAB9APOLB | |
| SCHEMBL8396071 | 0.87 | LTB4R2 (0.36) | RAB9ALMNAPTGDR2LTB4R2 | |
| SCHEMBL8396627 | 0.87 | RXRA (0.34) | KMT2ALMNALTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |