Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398292 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1HTTRAB9ALTB4R2 | |
| SCHEMBL8396315 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HTTRAB9ALTB4R2 | |
| SCHEMBL8395385 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LTB4R2MAPTKMT2A | |
| SCHEMBL8400205 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LTB4R2MAPTKMT2A | |
| SCHEMBL8399172 | 0.87 | LTB4R2 (0.45) | SMN1; SMN2LTB4R2NPC1MAPTKMT2A | |
| SCHEMBL8399213 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2LTB4R2KMT2A | |
| SCHEMBL8400187 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1RAB9ALTB4R2NPC1 | |
| SCHEMBL8399140 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1HTTRAB9ALTB4R2 | |
| SCHEMBL8398013 | 0.86 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HTTRAB9AEPHX2 | |
| SCHEMBL8396409 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1RAB9ALTB4R2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |