Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395141 | 0.92 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTEGFRERBB3LMNA | |
| SCHEMBL8396315 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8399213 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2ATP53KDM4E | |
| SCHEMBL8399265 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTALDH1A1KMT2ALTB4R2 | |
| SCHEMBL8395385 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTLMNATSHRALDH1A1 | |
| SCHEMBL8399172 | 0.87 | LTB4R2 (0.45) | SMN1; SMN2MAPTMEN1KMT2ATP53 | |
| SCHEMBL8399091 | 0.86 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPTLMNAALDH1A1HPGD | |
| SCHEMBL8399042 | 0.86 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRALDH1A1HPGDMEN1 | |
| SCHEMBL8396409 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNATSHRALDH1A1MEN1 | |
| SCHEMBL8396222 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |