Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399269 | 0.83 | MAPT (0.38) | SMN1; SMN2MAPTNPC1LMNAL3MBTL1 | |
| SCHEMBL8395692 | 0.82 | MAPT (0.36) | SMN1; SMN2MAPTNPC1LMNAL3MBTL1 | |
| SCHEMBL8397890 | 0.81 | RAB9A (0.37) | SMN1; SMN2MAPTNPC1LMNAL3MBTL1 | |
| SCHEMBL8399713 | 0.81 | AKR1B1 (0.45) | MAPT | |
| SCHEMBL8399428 | 0.80 | MEN1 (0.43) | SMN1; SMN2MAPTNPC1LMNAMAPK1 | |
| SCHEMBL8396660 | 0.79 | MEN1 (0.36) | SMN1; SMN2MAPTNPC1LMNAL3MBTL1 | |
| SCHEMBL8398930 | 0.79 | HDAC6 (0.48) | SMN1; SMN2MAPTNPC1LMNAL3MBTL1 | |
| SCHEMBL8396283 | 0.79 | SYK (0.45) | SMN1; SMN2MAPTNPC1L3MBTL1TDP1 | |
| SCHEMBL8395544 | 0.71 | GAA (0.43) | MAPTLMNAALDH1A1GAAMEN1 | |
| SCHEMBL8399348 | 0.71 | LTB4R2 (0.39) | MAPTLMNAL3MBTL1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |