Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395489 | 0.83 | AKR1B1 (0.39) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL8399268 | 0.83 | SMN1; SMN2 (0.37) | MAPTCACNA1BSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL8399274 | 0.82 | MEN1 (0.34) | SMN1; SMN2NPC1AKR1B1L3MBTL1 | |
| SCHEMBL8399713 | 0.82 | AKR1B1 (0.45) | MAPTAKR1B1 | |
| SCHEMBL8399262 | 0.82 | AKR1B1 (0.40) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL8400483 | 0.80 | AKR1B1 (0.44) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL8395435 | 0.80 | AKR1B1 (0.38) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL8399351 | 0.80 | AKR1B1 (0.46) | MAPTSMN1; SMN2NPC1RAB9AAKR1B1 | |
| SCHEMBL8396655 | 0.79 | HDAC6 (0.50) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A | |
| SCHEMBL8399257 | 0.79 | SYK (0.44) | MAPTSMN1; SMN2NPC1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |