⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703725 | 0.85 | ALDH1A1 (0.35) | — | |
| SCHEMBL4637291 | 0.82 | ALDH1A1 (0.33) | — | |
| SCHEMBL11671028 | 0.81 | — | — | |
| SCHEMBL706117 | 0.80 | KDM4E (0.35) | — | |
| SCHEMBL703249 | 0.80 | KDM4E (0.35) | — | |
| SCHEMBL8975138 | 0.79 | — | — | |
| SCHEMBL11455842 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL27710256 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL13089420 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL5359673 | 0.78 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939575-A | REMOVING THE BY-PRODUCT ACYL CHLORIDE BY SALT FORMING QUANTITATIVELY WITH METAL CARBOXYLATE | HUELS AKTIENGESELLSHAFT (DE) | 1999-08-17 | — | — | US | disclosed |
| US-5852206-A | Process for removing residual acidic chlorine from acyloxysilanes | HUELS AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0845473-A2 | Process for removing residual acidic chlorine from carbonyloxysilan | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-06-03 | — | — | EP | disclosed |
| EP-0845470-A2 | Continuous process for preparing carbonyloxysilan | HÜLS AKTIENGESELLSCHAFT (DE) | 1998-06-03 | — | — | EP | disclosed |
| EP-0509213-B1 | Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides | HUELS CHEMISCHE WERKE AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| US-5187291-A | Reacting monocarboxylic anhydrides with organochlorosilanes in presence of organic bases, then vacuum distillation | HULS AKTIENGESELLSCHAFT (DE) | 1993-02-16 | — | — | US | disclosed |
| EP-0509213-A1 | Process for the simultaneous and continuous production of carbonyloxy silanes and of carboxylic acid chlorides | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-10-21 | — | — | EP | disclosed |
| US-4045459-A | METHYL-SILANDIOL | CIBA-GEIGY CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |