SCHEMBL4637291

SCHEMBL4637291

CC(=O)O[Si](C)(CCl)OC(C)=O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8399353 0.82
SCHEMBL4636155 0.81
SCHEMBL705827 0.80 ALDH1A1 (0.35) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL703725 0.80 ALDH1A1 (0.35) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL4636526 0.78 ALDH1A1 (0.33) ALDH1A1HSD17B10TSHRLMNA
SCHEMBL27723019 0.78 ALDH1A1 (0.33) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL3791516 0.78 ALDH1A1 (0.39) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL2903187 0.76 HSD17B10 (0.38) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL15661904 0.76 ALDH1A1 (0.32) ALDH1A1HSD17B10TDP1TSHRLMNA
SCHEMBL13089258 0.76 ALDH1A1 (0.32) ALDH1A1HSD17B10TDP1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2567986-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2022-04-13 EP claimed
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US claimed
EP-2567986-B1 OLEFIN POLYMERIZATION CATALYST AND PREPARATION METHOD AND USE THEREOF PETROCHINA CO LTD (CN) 2022-04-13 EP disclosed
US-8716417-B2 Olefin polymerization catalyst and preparation method and use thereof PETROCHINA COMPANY LIMITED (CN) 2014-05-06 US disclosed
CN-100509825-C Organofunctional surface-modified metal oxides WACKER CHEMIE GMBH (DE) 2009-07-08 CN disclosed
US-20080255354-A1 Method for Producing Alkoxysilyl Methyl Isocyanurates WACKER CHEMIE AG (DE) 2008-10-16 US disclosed
EP-1853613-B1 METHOD FOR PRODUCING ALKOXYSILYL METHYL ISOCYANURATES WACKER CHEMIE AG (DE) 2008-07-02 EP disclosed
CN-101133069-A Method for producing alkoxysilyl methyl isocyanurates WACKER CHEMIE AG (DE) 2008-02-27 CN disclosed
EP-1853613-A1 METHOD FOR PRODUCING ALKOXYSILYL METHYL ISOCYANURATES Wacker Chemie AG (DE) 2007-11-14 EP disclosed
US-7276615-B2 Organofunctional surface-modified metal oxides WACKER CHEMIE AG (DE) 2007-10-02 US disclosed
WO-2006092324-A1 METHOD FOR PRODUCING ALKOXYSILYL METHYL ISOCYANURATES WACKER CHEMIE AG (DE) 2006-09-08 WO disclosed
EP-1473296-B1 Organofunctional surface modified metal oxides WACKER CHEMIE AG (DE) 2006-08-02 EP disclosed
CN-1572794-A Organofunctional surface-modified metal oxides WACKER CHEMIE GMBH (DE) 2005-02-02 CN disclosed
US-20040220419-A1 Organofunctional surface-modified metal oxides WACKER-CHEMIE GMBH (DE) 2004-11-04 US disclosed
EP-1473296-A1 Organofunctional surface modified metal oxides Wacker-Chemie GmbH (DE) 2004-11-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080255354-A1 Method for Producing Alkoxysilyl Methyl Isocyanurates TST, ICMT, AS3MT ALDH1A1 3250/4885HSD17B10 1604/4885TDP1 4051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.