Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LIG1 | P18858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6044198 | 0.87 | SLC6A3 (0.50) | ALDH1A1HSP90AA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL18493694 | 0.86 | CA12 (0.43) | ALDH1A1HSP90AA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL385145 | 0.85 | LIG1 (0.68) | ALDH1A1HSP90AA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL30195826 | 0.85 | LIG1 (0.68) | ALDH1A1HSP90AA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9374397 | 0.84 | TSHR (0.61) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12070045 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HSP90AA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL6042536 | 0.81 | KDM4E (0.49) | ALDH1A1HSP90AA1MAPTCYP1A2CYP2C9 | |
| SCHEMBL1524367 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP1A2CYP2C9HPGD | |
| SCHEMBL30961481 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTCYP1A2CYP2C9HPGD | |
| SCHEMBL1989129 | 0.81 | HCRTR1 (0.65) | ALDH1A1HSP90AA1MAPTSLC6A3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4107148-A | Powder coating composition comprising a mixture of a polyester and plural silicone compounds | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1978-08-15 | — | — | US | claimed |
| EP-0667854-B1 | PEPTIDYL ACTIVATED KETONE INHIBITORS CONTAINING NATURAL AND UNNATURAL PEPTIDE SEQUENCES | PROTOTEK INC (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0667854-A1 | PEPTIDYL ACTIVATED KETONE INHIBITORS CONTAINING NATURAL AND UNNATURAL PEPTIDE SEQUENCES | PROTOTEK, INC., (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0667854-A4 | PEPTIDYL ACTIVATED KETONE INHIBITORS CONTAINING NATURAL AND UNNATURAL PEPTIDE SEQUENCES. | PROTOTEK INC (US) | 1995-07-04 | — | — | EP | disclosed |
| US-5374623-A | Cysteine protease inhibitors effective for in vivo use | PROTOTEK, INC. (US) | 1994-12-20 | — | — | US | disclosed |
| WO-1994004172-A1 | PEPTIDYL ACTIVATED KETONE INHIBITORS CONTAINING NATURAL AND UNNATURAL PEPTIDE SEQUENCES | PROTOTEK, INC. (US) | 1994-03-03 | — | — | WO | disclosed |
| US-4107148-A | Powder coating composition comprising a mixture of a polyester and plural silicone compounds | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1978-08-15 | — | — | US | disclosed |