Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314986 | 0.86 | ADRB2 (0.60) | TSHRALDH1A1HSD17B10TBXAS1CDC25B | |
| SCHEMBL536025 | 0.85 | TSHR (0.71) | TSHRALDH1A1HSD17B10TBXAS1CDC25B | |
| SCHEMBL8399357 | 0.84 | ALDH1A1 (0.54) | TSHRALDH1A1HSD17B10HCRTR1MAPT | |
| SCHEMBL11444937 | 0.84 | ALDH1A1 (0.64) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| Bicarbonate SCHEMBL5184189 | 0.82 | TSHR (0.67) | TSHRALDH1A1HSD17B10TBXAS1HCRTR1 | |
| SCHEMBL16674272 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10TBXAS1CDC25B | |
| SCHEMBL9969538 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10TBXAS1CDC25B | |
| SCHEMBL6575655 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10TBXAS1CDC25B | |
| SCHEMBL29141053 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10TBXAS1CDC25B | |
| Acetic Acid SCHEMBL4244149 | 0.81 | TSHR (0.65) | TSHRALDH1A1HSD17B10TBXAS1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586233-A | Preparation and application of N- [ (1H-indol-4-yl) alkyl ] benzamide compound | 沈阳药科大学 | 2024-02-23 | — | — | CN | disclosed |
| EP-0297621-B1 | Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA (IT) | 1994-09-21 | — | — | EP | disclosed |
| US-4988701-A | Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1991-01-29 | — | — | US | disclosed |
| EP-0297621-A2 | Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions containing them | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1989-01-04 | — | — | EP | disclosed |