Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPM1A | P35813 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982322 | 0.81 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL8399385 | 0.73 | SIGMAR1 (0.61) | SIGMAR1CYP2D6 | |
| SCHEMBL4981507 | 0.71 | SIGMAR1 (0.73) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL4985918 | 0.71 | KDM4E (0.64) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL6717107 | 0.69 | SIGMAR1 (0.42) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL8742588 | 0.69 | SIGMAR1 (0.59) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL27844570 | 0.69 | SIGMAR1 (0.56) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL8152318 | 0.69 | MCL1 (0.58) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL3925314 | 0.68 | ALDH1A1 (0.60) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL6728890 | 0.68 | SIGMAR1 (0.41) | KMT2AMEN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |