Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4982326 | 0.81 | SIGMAR1 (0.90) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL13138486 | 0.74 | SIGMAR1 (0.56) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL8399382 | 0.73 | KMT2A (0.48) | SIGMAR1CYP2D6 | |
| SCHEMBL4981507 | 0.71 | SIGMAR1 (0.73) | SIGMAR1 | |
| SCHEMBL8742588 | 0.69 | SIGMAR1 (0.59) | SIGMAR1 | |
| SCHEMBL27844570 | 0.69 | SIGMAR1 (0.56) | SIGMAR1CYP2D6 | |
| SCHEMBL8152318 | 0.69 | MCL1 (0.58) | SIGMAR1TP53TSHR | |
| SCHEMBL16887967 | 0.69 | SIGMAR1 (0.71) | SIGMAR1TP53CYP2D6TSHRTHPO | |
| SCHEMBL4982322 | 0.67 | ALDH1A1 (0.50) | SIGMAR1 | |
| SCHEMBL28782554 | 0.67 | SIGMAR1 (0.53) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |