Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 2/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525635 | 0.82 | JAK2 (0.46) | ITGB3ITGAVMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL8468698 | 0.80 | KDM4E (0.44) | ITGB3ITGAVMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL8518891 | 0.78 | ITGB3 (0.42) | ITGB3ITGAVMAPK1ALDH1A1KDM4E | |
| SCHEMBL7916963 | 0.74 | ITGB3 (0.51) | ITGB3ITGAVMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL7916970 | 0.74 | ITGB3 (0.51) | ITGB3ITGAVMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL7397715 | 0.72 | ITGB3 (0.45) | ITGB3ITGAV | |
| SCHEMBL7397708 | 0.72 | ITGB3 (0.45) | ITGB3ITGAV | |
| SCHEMBL4798163 | 0.70 | EPHX2 (0.53) | EPHX2GAADRD2KMT2A | |
| SCHEMBL17916932 | 0.70 | EPHX2 (0.53) | EPHX2GAADRD2KMT2A | |
| SCHEMBL4798177 | 0.70 | EPHX2 (0.53) | EPHX2GAADRD2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |