Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401411 | 0.85 | PKM (0.46) | — | |
| SCHEMBL9084289 | 0.85 | THRB (0.47) | THRBMAPTTDP1SMN1; SMN2 | |
| SCHEMBL9158313 | 0.83 | — | — | |
| SCHEMBL8786216 | 0.80 | SMN1; SMN2 (0.45) | MAPTTDP1SMN1; SMN2 | |
| SCHEMBL8402590 | 0.78 | TP53 (0.42) | THRBMAPTSMN1; SMN2 | |
| SCHEMBL8202905 | 0.76 | NPC1 (0.46) | SMN1; SMN2 | |
| SCHEMBL8196513 | 0.76 | NPC1 (0.46) | SMN1; SMN2 | |
| SCHEMBL8401455 | 0.75 | LMNA (0.47) | MAPTSMN1; SMN2 | |
| SCHEMBL9082748 | 0.75 | PKM (0.47) | MAPTSMN1; SMN2 | |
| SCHEMBL9157930 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929107-A | INHIBITORS OF ACYL-COA:CHOLESTEROL ACYLTRANSFERASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5492929-A | ENZYME INHIBITORS, ANTICHOLESTEROL AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-20 | — | — | US | disclosed |
| EP-0602598-A1 | 3-Phenylindolyl-, -benzofuranyl- and -benzothienyl- alkylcarboxanilides, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1994-06-22 | — | — | EP | disclosed |