Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8401455 | 0.80 | LMNA (0.47) | ALDH1A1NPC1RAB9AKDM4ECASP3 | |
| SCHEMBL8403485 | 0.77 | MAP2 (0.43) | ALDH1A1NPC1RAB9AKDM4ECASP3 | |
| SCHEMBL8398887 | 0.73 | TP53 (0.43) | RAB9AKDM4EMAP2LMNAMAPT | |
| SCHEMBL6940805 | 0.73 | MCL1 (0.62) | ALDH1A1NPC1RAB9AKDM4ECASP3 | |
| SCHEMBL8402590 | 0.71 | TP53 (0.42) | KDM4EMAP2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8403480 | 0.71 | S1PR4 (0.44) | ALDH1A1KDM4EMAP2HPGDLMNA | |
| SCHEMBL8398986 | 0.70 | S1PR2 (0.45) | ALDH1A1NPC1KDM4ECASP3SENP8 | |
| SCHEMBL8784953 | 0.70 | MAOA (0.51) | ALDH1A1NPC1RAB9AKDM4ECASP3 | |
| SCHEMBL8403484 | 0.70 | KDM4E (0.60) | ALDH1A1NPC1RAB9AKDM4ECASP3 | |
| SCHEMBL8784765 | 0.70 | LMNA (0.49) | ALDH1A1NPC1RAB9AKDM4ECASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929107-A | INHIBITORS OF ACYL-COA:CHOLESTEROL ACYLTRANSFERASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |