SCHEMBL8399491

SCHEMBL8399491

CCN(CC)c1ccc(C2C3CC(C)CC2C3=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.42
L3MBTL1 Q9Y468 5/20 0.42
GFER P55789 3/20 0.42
MAPK1 P28482 2/20 0.42
RECQL P46063 2/20 0.42
TSHR P16473 2/20 0.42
PSMD14 O00487 1/20 0.42
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
ALDH3A1 P30838 1/20 0.40
ALDH1A3 P47895 1/20 0.40
RAB9A P51151 3/20 0.39
MEN1 O00255 6/20 0.39
KMT2A Q03164 6/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.38
NPC1 O15118 1/20 0.38
ALOX15 P16050 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15514380 0.75 ALDH1A1 (0.49) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL5685504 0.71 ALOX15 (0.47) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL12972037 0.69 KDM1A (0.54) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL813293 0.69 ALOX15 (0.48) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL14679717 0.69 ALDH1A1 (0.54) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL5146728 0.66 ALDH1A1 (0.50) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL1735497 0.66 ALDH1A1 (0.74) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL5664801 0.66 ALDH1A1 (0.45) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL14489571 0.66 ALDH1A1 (0.53) ALDH1A1L3MBTL1GFERMAPK1RECQL
SCHEMBL28794475 0.65 ALDH1A1 (0.45) ALDH1A1L3MBTL1GFERMAPK1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0505161-B1 Photosensitive polymer composition SHINETSU CHEMICAL CO (JP) 1999-06-16 EP disclosed
US-5292619-A Polyamide and a urea compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1994-03-08 US disclosed
EP-0505161-A1 Photosensitive polymer composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-09-23 EP disclosed