Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DUT | P33316 | 5/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2899640 | 0.76 | ALDH1A1 (0.59) | KDM4ELMNAALDH1A1L3MBTL1DUT | |
| SCHEMBL20042582 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AKDM4ENPC1NR2F2 | |
| SCHEMBL18313849 | 0.72 | KDM4E (0.60) | SMN1; SMN2RAB9AKDM4ENPC1NR2F2 | |
| SCHEMBL11983580 | 0.72 | ALDH1A1 (0.58) | KDM4ELMNAALDH1A1L3MBTL1DUT | |
| SCHEMBL11710750 | 0.72 | ALDH1A1 (0.58) | KDM4ELMNAALDH1A1L3MBTL1DUT | |
| SCHEMBL6280756 | 0.71 | L3MBTL1 (0.51) | RAB9AKDM4ENPC1LMNAALDH1A1 | |
| SCHEMBL17830465 | 0.71 | MAPT (0.53) | SMN1; SMN2RAB9AKDM4ENPC1NR2F2 | |
| SCHEMBL15030329 | 0.71 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AKDM4ENPC1NR2F2 | |
| SCHEMBL19370629 | 0.71 | IDO1 (0.51) | SMN1; SMN2RAB9AKDM4ENPC1LMNA | |
| SCHEMBL667245 | 0.69 | ALDH1A1 (0.59) | SMN1; SMN2KDM4ELMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962460-A | CONTROLLING CANCER GROWTH | NATIONAL SCIENCE COUNCIL (TAIWAN) (TW) | 1999-10-05 | — | — | US | disclosed |