Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 18/20 | 0.67 |
| ▸ | NOS3 | P29474 | 17/20 | 0.67 |
| ▸ | NOS2 | P35228 | 16/20 | 0.67 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833967 | 0.81 | NOS1 (1.00) | NOS1NOS3NOS2HTR1B | |
| SCHEMBL5833873 | 0.80 | NOS1 (0.88) | NOS1NOS3NOS2HTR1B | |
| SCHEMBL5833992 | 0.79 | NOS1 (0.86) | NOS1NOS3NOS2HTR1B | |
| SCHEMBL5833200 | 0.79 | NOS3 (0.61) | NOS1NOS3NOS2 | |
| SCHEMBL5834017 | 0.78 | NOS3 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL5833741 | 0.78 | NOS3 (0.63) | NOS1NOS3NOS2 | |
| SCHEMBL5833697 | 0.78 | NOS3 (0.76) | NOS1NOS3NOS2 | |
| SCHEMBL5833909 | 0.77 | NOS3 (0.98) | NOS1NOS3NOS2 | |
| SCHEMBL5833522 | 0.77 | NOS1 (0.78) | NOS1NOS3NOS2HTR1B | |
| SCHEMBL7082993 | 0.77 | NOS1 (0.86) | NOS1NOS3NOS2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | PFIZER INC | 2004-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | NOS1, NOS3, NPBWR1 | NOS1 1/4885NOS3 2/4885NOS2 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.