Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 16/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.41 |
| ▸ | ITGAV | P06756 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403456 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2BITGAV | |
| SCHEMBL8898789 | 0.75 | F2 (0.39) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8899096 | 0.74 | ITGB3 (0.39) | ITGB3ITGA2BF2 | |
| SCHEMBL8401186 | 0.74 | ITGB3 (0.45) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8398958 | 0.70 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL8519494 | 0.69 | ITGB3 (0.39) | ITGB3ITGA2BITGAVKDM4EF2 | |
| SCHEMBL8896265 | 0.67 | ITGB3 (0.45) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8402359 | 0.67 | KDM4E (0.36) | ITGB3ITGA2BITGAVKDM4EMEN1 | |
| SCHEMBL8401220 | 0.66 | ITGB3 (0.43) | ITGB3ITGA2BITGAVF2 | |
| SCHEMBL8401242 | 0.65 | ITGB3 (0.51) | ITGB3ITGA2BITGAVF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939412-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5693636-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-02 | — | — | US | disclosed |